Avicor combats Covid-19 pandemic

Avicor, reported by HVG (Weekly World Economy) the Hungarian leading economic and political weekly, is working on synthetizing potential drug candidate molecules which inhibit the enzyme responsible for the viral entry of Covid-19 together with a German company.

Avicor Ltd. successfully developed…

Avicor Ltd. successfully developed several new products in the frame of a Hungarian R&D grant (KFI_16-1-2017-0105) for specific enrichment of nucleic acids deriving from diverse biological samples specific for human, bacterial, fungal and viral nucleic acids.

Electron paramagnetic resonance spectroscopic studies of the electron transfer reaction of Hantzsch ester and a pyrylium salt

Sebők-Nagy K, Rózsár D, L. G. Puskás LG, Balázs Á and Páli T Abstract The oxidation of Hantzsch ester by a pyrylium cation takes place via electron–proton–electron transfer. The reaction was investigated with EPR spectroscopy using TEMPO and DMPO for inhibition and spin trapping, respectively, of the radicals appearing during the reaction. The present in-depth EPR study ...

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[cz_title bline="cz_line_both_side" id="cz_20285" cz_title="" css_right_line_left="1px" sk_lines="background-color:rgba(0,69,160,0.3);width:30px;height:4px;top:0px;left:1px;" sk_lines_con="height:4px;top:5px;"] Hit discovery [/cz_title] Our screening capacity is app. 5000 interaction studies weekly. [cz_title bline="cz_line_both_side" id="cz_70637" cz_title="" css_right_line_left="1px" sk_lines="background-color:rgba(0,69,160,0.3);width:30px;height:4px;top:0px;left:1px;" sk_lines_con="height:4px;top:5px;"] Target identification [/cz_title] Our target discovery services are based on high throughput screening assays based on biochemical array or protein-small molecule interaction. We apply 2 different technologies: 1) proprietary surface ...

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KFI-16 grant (KFI_16-1-2017-0105)

Development of a series of specific nucleic acid enrichment products for sensitive pathogens detection In conventional microbiological diagnostics, the presence of an infectious agent and its antibiotic resistance is detected by a conventional propagation process, which is a slow and non-sensitive. The consortium is planning to produce a series of reagents that can specially enrich …

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Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

Kanizsai I, Madácsi R, Hackler L Jr, Gyuris M, Szebeni GJ, Huzián O, Puskás LG. Abstract The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection. Based on our previous findings we set out to optimize the scaffold for cytoprotective activity for its potential ...

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Avicor’s highly effective fluorophore AC-202 in Biotechnologies for Biofuels Journal

Researchers at Aix-Marseille University (France) demonstrated that our new, blue fluorescent dye, AC-202 is effective in both green algae Chlamydomonas reinhardtii and pennate diatom Phaeodactylum tricornutum. They also  prooved that after minimal sample preparation, it can label lipid droplets induced by nitrogen starvation or by inhibitors of the TOR (target of rapamycin) kinase. They found that AC-202 benefits ...

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