Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

Kanizsai I, Madácsi R, Hackler L Jr, Gyuris M, Szebeni GJ, Huzián O, Puskás LG. Abstract The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection. Based on our previous findings we set out to optimize the scaffold for cytoprotective activity for its potential ...

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