Development of a series of specific nucleic acid enrichment products for sensitive pathogens detection

In conventional microbiological diagnostics, the presence of an infectious agent and its antibiotic resistance is detected by a conventional propagation process, which is a slow and non-sensitive. The consortium is planning to produce a series of reagents that can specially enrich clinical or environmental specimens. A separate reagent kit will be produced for the enrichment of bacterial, fungal and viral nucleic acids, which will be compatible with different genomic methods. The products will be silicone and magnetic microspheres based with special molecules on their surface, that are capable of specifically binding human, bacterial, fungal, and viral nucleic acids. The products will be capable of use in automated equipment.

Research grants

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